Children's liquid laxative for cats3/17/2024 ![]() ![]() įurthermore, the summary of evidence by the Canadian Agency for Drugs and Technologies in Health involved a comprehensive search of 367 citations from the literature. Nevertheless, docusate continues to be one of the most frequently prescribed laxatives. Numerous systematic reviews examining the efficacy of docusate have yielded no significant evidence to support its use. Consequently, the study concluded that the use of docusate in managing constipation in hospice patients should be evaluated individually. The results indicated no significant differences between the docusate and placebo groups in the assessed outcomes. A total of 74 hospice patients were included in the study and were assigned to receive either docusate and senna or placebo and senna for 10 days. Ī randomized, double-blind, placebo-controlled trial was conducted to assess the efficacy of docusate in managing constipation in hospice patients. Stool softening typically occurs within 12 to 72 hours after initiating therapy with docusate. Notably, several studies have demonstrated that docusate is ineffective for treating constipation in individuals. As a result, docusate is not featured on the FDA's rundown of authorized drugs, and there are no approved indications for its use.Īccording to the product monograph, docusate is indicated for use when peristaltic stimulants are contraindicated, aiming to alleviate difficult or painful defecation.ĭocusate facilitates the passage of hard stools, which can benefit patients with painful anorectal conditions or cardiac comorbidities. Food and Drug Administration (FDA) has not determined the safety and efficacy of docusate for managing constipation in individuals. ![]() National Library of Medicine, DailyMed resource. Docusate is classified as an over-the-counter (OTC) medication and has the marketing status of "OTC monograph not final," according to the U.S. They come in the form of either docusate sodium or docusate calcium salts. ĭocusate, also known as dioctyl sulfosuccinate, is of 2 types that can be administered orally. ![]() Lubiprostone is a chloride channel activator that stimulates intestinal secretion and improves motility. The different classes of commonly used laxatives for treating and managing constipation are listed below. If these adjustments do not effectively address constipation, then the use of laxatives becomes necessary. The dietary changes should promote increased consumption of fluid and fiber-rich foods. Moreover, increased physical activity has been linked to lower rates of constipation. Clinicians must clarify to patients that not having a daily bowel movement is neither abnormal nor necessary. The non-pharmacological management of chronic constipation begins with patient education and adjusting dietary and lifestyle habits. ![]() However, patients often describe constipation with a broader range of symptoms, including difficulty passing stool, firmer stool consistency, abdominal cramping, and a feeling of incomplete stool evacuation. Most clinicians commonly define constipation as infrequent bowel movements, usually less than 3 per week. There is no universally applicable definition of constipation. Constipation is a prevalent complaint encountered in clinical practice, affecting approximately 16% of all adults and 33% of adults 60 and older. ![]()
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